Somatic Genomic Variations in Early Human Prenatal Development
نویسندگان
چکیده
منابع مشابه
Somatic Genomic Variations in Early Human Prenatal Development
Only 25 to 30% of conceptions result in a live birth. There is mounting evidence that the cause for this low fecundity is an extremely high incidence of chromosomal rearrangements occurring in the cleavage stage embryo. In this review, we gather all recent evidence for an extraordinary degree of mosaicisms in early embryogenesis. The presence of the rearrangements seen in the cleavage stage emb...
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In the mature chorion, one of the membranes that exist during pregnancy between the developing fetus and mother, human placental cells form highly specialized tissues composed of mesenchyme and floating or anchoring villi. Using fluorescence in situ hybridization, we found that human invasive cytotrophoblasts isolated from anchoring villi or the uterine wall had gained individual chromosomes; h...
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ژورنال
عنوان ژورنال: Current Genomics
سال: 2010
ISSN: 1389-2029
DOI: 10.2174/138920210793175967